Dissertation Writing service Buy Dissertation Online essay writing service cheap essay writing Curriculum | Postgraduate Program in Technological Development and Innovation in Medicines (PPgDITM)

Curriculum

 
INOVAÇÃO TECNOLÓGICA EM MEDICAMENTOS
  Code Discipline/Activity Hours
[+] DIT0005 BIOTECHNOLOGY APPLIED TO RESEARCH AND DEVELOPMENT OF MEDICINES 30h
INTRODUCTION TO BIOTECHNOLOGY: CONCEPT AND HISTORICAL PERSPECTIVE. BIOTECHNOLOGY AND MULTIDISCIPLINARITY. GENERAL AND HEALTH-RELATED APPLICATIONS. MOLECULAR BIOTECHNOLOGY. BIOTECHNOLOGY IN RESEARCH AND DEVELOPMENT OF MEDICINES. GENOMIC AND CDNA LIBRARIES. CLONING. GENOMICS. PROTEOMICS. TRANSCRIPTOMICS. TRANSGENICS. VACCINES. SERUMS. GENE THERAPY. STEM CELLS. BIOINFORMATICS. BIOETHICS.
[+] DIT0009 PRECLINICAL PHARMACOLOGICAL AND TOXICOLOGICAL TESTS 30h
CONCEPT OF TOXIC AGENTS (XENOBIOTIC), TOXICITY AND INTOXICATION. METHODOLOGY APPLIED TO THE UNDERSTANDING OF THE TOXIC POTENTIAL OF XENOBIOTICS. STUDY OF THE EVALUATION OF ACUTE, SUB-ACUTE, SUB-CHRONIC AND CHRONIC TOXICITY, IN ADDITION TO STUDIES IN THE REPRODUCTIVE SPHERE WITH A VIEW TO UNDERSTANDING THE ACTIVITY OF XENOBIOTICS ON PREGNANCY AND ON THE EXPOSED OFFSPRING.
[+] DIT0017 CHROMATOGRAPHIC METHODS APPLIED TO THE DEVELOPMENT OF MEDICINES 45h
DEVELOPMENT AND VALIDATION OF CHROMATOGRAPHIC ANALYTICAL METHODS, APPLIED TO THE CONTROL AND DEVELOPMENT OF PHARMACEUTICAL PRODUCTS. STUDY OF THE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY TECHNIQUE, OPERATION OF A LIQUID CHROMATOGRAPHY SYSTEM, HANDLING OF COLUMNS AND CARE, DETECTORS, INCLUDING MAINTENANCE ROUTINES AND PROCEDURES FOR THE DIAGNOSIS AND RESOLUTION OF PROBLEMS. FUNDAMENTAL PRINCIPLES OF GASEOUS CHROMATROGRAPHY. STATIONARY AND MOBILE STAGE, EQUILIBRIUM AMONG THE STAGES. THEORETICAL PLATE, RETENTION TIME. CHROMATOGRAMS, INSTRUMENTATION, TYPES OF COLUMNS AND DETECTORS. QUALITATIVE AND QUANTITATIVE MEASURES. GASEOUS CHROMATOGRAPHY VERSUS MASS SPECTROMETRY: APPLICATION IN THE PHARMACEUTICAL SCIENCES. IONIZATION METHODS IN MASS SPECTROMETRY. MASS ANALYZERS (QUADRUPOLES, ION TRAPS AND MAGNETIC SECTORS. HYBRID DRAWINGS). INTERFACING OF MASS SPECTROMETRY WITH CHROMATOGRAPHIC TECHNIQUES.
[+] DIT0018 ANALYTICAL METHODOLOGIES APPLIED TO CHEMICAL AND BIOLOGICAL MATRICES 60h
STUDY OF THE METHODS OF PREPARATION OF SAMPLES USED IN THE PROCEDURES OF ANALYSIS OF SIMPLE OR COMPLEX PHARMACEUTICAL SAMPLES. EXAMINING AND FOCUSING ON THE PROCEDURES OF EXTRACTION AND CONCENTRATION OF PHARMACEUTICALS OF SOLID, LIQUID AND GASEOUS MATRICES THROUGH THE MICROWAVE-ASSISTED EXTRACTION, ACCELERATED SOLVENT EXTRACTION, ULTRASONIC EXTRACTION, SUPERCRITICAL FLUID EXTRACTION, SOLID PHASE EXTRACTION, MICROEXTRACTIONS, PURGE AND TRAP, PIROLYSIS, HEADSPACE, AMONG OTHERS.
[+] DIT0024 NATURAL PRODUCTS AS SOURCE OF NEW PHARMACEUTICALS 30h
CLASSES OF SECONDARY METABOLITES ACCORDING TO THEIR STRUCTURE AND BIOGENETIC RELATIONSHIPS. MAIN SPECIES, OR FAMILY OF PLANTS, AS SOURCES OF NATURAL PRODUCTS WITH POTENTIAL PHARMACEUTICAL USE. TECHNIQUES OF EXTRACTION, ANALYSIS AND SEPARATION (MODERN CHROMATOGRAPHIC TECHNIQUES), AND CHARACTERIZATION OF SECONDARY METABOLITES (MAIN SPECTROSCOPIC TECHNIQUES). PREPARATION OF REACTIONAL DERIVATIVES AND DETERMINATION OF THE RELATIONSHIP BETWEEN CHEMICAL STRUCTURE AND PHARMACOLOGICAL ACTIVITY.
[+] DIT0025 INTELLECTUAL PROPERTY IN THE PHARMACEUTICAL INDUSTRY 60h
LEGISLATION. TECHNOLOGICAL PROSPECTION. CONTRACTS AND TECHNOLOGY TRANSFER. INTELLECTUAL PROPERTY LAW. PATENT BREAKING.
[+] DIT0030 TECHNOLOGY OF PHARMACEUTICAL DOSAGE FORMS 60h
MAIN BREAKTHROUGHS IN THE RESEARCH AND DEVELOPMENT OF PHARMACEUTICAL DOSAGE FORMS. DISCUSSION OF THE MAIN FOUNDATIONS FOR THE PRODUCTION OF SOLID DOSAGE FORMS AND DISPERSE SYSTEMS AND THEIR BIOPHARMACEUTICAL ASPECTS. NEW EXCIPIENTS AND PROCESSES. MODIFIED RELEASE DOSAGE FORMS.
[+] DIT0031 TECHNOLOGY OF SYNTHETIC RAW MATERIALS 60h
TECHNOLOGICAL ASPECTS INVOLVING THE SYNTHESIS OF PHARMACEUTICALS, FROM THE SELECTION OF THE SYNTHETIC STRATEGY UP TO THE VALIDATION OF THE OBTAINMENT PROCESS. DISCUSSION OF THE EXPERIMENTATION PARAMETERS IN LABORATORIAL SCALE AND PARAMETERIZATION OF OPERATIONS DURING THE TRANSPOSITION OF SCALE. CASE STUDY: NEVIRAPINA.
[+] DIT0041 CLINICAL ASSESSMENT OF PHARMACEUTICALS 30h
OVERVIEW OF THE CLINICAL RESEARCH IN BRAZIL AND AROUND THE WORLD. NOTIONS OF GOOD CLINICAL PRACTICES. STAGES OF THE CLINICAL RESEARCH. RESEARCH CENTER: STRUCTURE AND OPERATION. REGISTRATION STANDARDS. DEVELOPMENT OF PROTOCOLS OF PHARMACOLOGICAL-CLINICAL TESTS. ADVERSE EVENTS. REGULATORY AUTHORITIES. CONDUCTION, MONITORING AND AUDIT OF PHARMACOLOGICAL-CLINICAL TESTS. ETHICAL AND LEGAL ASPECTS OF THE PHARMACOLOGICAL-CLINICAL TESTS.
[+] DIT0042 CLINICAL PHARMACOKINETICS 45h
ESTIMATION AND INTERPRETATION OF PHARMACOKINETIC PARAMETERS (ABSORPTION, DISTRIBUTION, METABOLISM AND ELIMINATION) OBTAINED IN CLINICAL TESTS AFTER THE EXTRAVASCULAR AND INTRAVASCULAR ADMINISTRATION. STUDY OF THE PHARMACEUTICAL-ORGANISM INTERACTION, THROUGH MATHEMATICAL MODELS. THE MOST RELEVANT FACTORS RELATED TO THE INTRA-INDIVIDUAL AND INTER-INDIVIDUAL VARIABILITY IN THE KINETIC DISPOSITION OF PHARMACEUTICALS. PREVENTION AND MODIFICATION OF THE PHARMACOKINETIC VARIABLES FOR THE OPTIMIZATION OF THERAPEUTIC REGIMES.
[+] DIT1001 DOCTORAL THESIS 0h
DOCTORAL THESIS
[+] DIT1002 DOCTORAL DEGREE QUALIFYING EXAM 0h
DOCTORAL DEGREE QUALIFYING EXAM
[+] DIT1003 ENGLISH LANGUAGE PROFICIENCY TEST 0h
ENGLISH LANGUAGE PROFICIENCY TEST
[+] DIT1004 SPANISH LANGUAGE PROFICIENCY TEST 0h
SPANISH LANGUAGE PROFICIENCY EXAM
[+] DIT0001 BIOPHARMACEUTICAL ASPECTS APPLIED TO THE RESEARCH & DEVELOPMENT AND REGISTRATION OF MEDICINES 30h
DISCUSSION OF THE PHYSICAL-CHEMICAL, PHYSIOLOGICAL AND TECHNOLOGICAL FACTORS AFFECTING THE BIOAVAILABILITY OF MEDICINES. BIOPHARMACEUTICAL CLASSIFICATION SYSTEM. METHODS OF ASSESSMENT OF THE IN VITRO / IN VIVO CORRELATION, BIOAVAILABILITY OF MEDICINES, BIOEQUIVALENCE AND PHARMACEUTICAL EQUIVALENCE. REGISTRATION OF REFERENCE, GENERIC AND SIMILAR MEDICINES.
[+] DIT0002 EXPERIMENTAL ASSESSMENT IN THE IMMEDIATE HYPERSENSITIVITY THERAPY 30h
TO PROVIDE THE CONCEPTS OF LOCAL AND SYSTEMIC ANAPHYLAXIS, ATOPY, IMMUNOGLOBULIN E (IGE), MASTOCYTES, ITS, EOSINOPHILS, CELL RECEPTORS INVOLVED IN THE IMMEDIATE HYPERSENSITIVITY (CD23 AND FC EPSLONRI), HISTAMINE, LEUKOTRIENES, CYTOKINES (IL-4, IL-5, IL-13, IFN-GAMA), EXPERIMENTAL ASTHMA. ANTI-INFLAMATORY ACTIVITY OF PHARMACEUTICALS. DESENSITIZATION. ACTIVITY OF AGENTS WHICH OPERATE IN THE IMMUNOMODULATION.
[+] DIT0003 BIOSTATISTICS APPLIED TO RESEARCH & DEVELOPMENT OF MEDICINES 30h
ORGANIZATION OF THE MEDICAL RESEARCH: DESCRIPTIVE AND COMPARATIVE STUDIES, PLANNING OF EXPERIMENTS (COMPARISON OF 2 GROUPS AND OF MORE THAN 2 GROUPS), DATA COLLECTION. PRESENTATION OF DATA AND DESCRIPTIVE ANALYSIS. NOTIONS OF PROBABILITY AND ASSESSMENT OF DIAGNOSTIC TESTS. PROBABILITY DISTRIBUTIONS. HYPOTHESIS TESTING FOR THE COMPARISON OF 2 GROUPS. VARIANCE ANALYSIS. RELATIVE RISK AND ODDS RATIO. NOTIONS OF SAMPLING. CORRELATION AND REGRESSION ANALYSIS.
[+] DIT0004 BIOPOLYMERS 30h
CHEMICAL STRUCTURE OF THE POLYMERS USED AS BIOMATERIALS AND INFLUENCE OF THE PHYSICAL-CHEMICAL PROPERTIES OF THESE POLYMERS ON THEIR BEHAVIOR AS CARRIERS OR VECTORS OF PHARMACEUTICALS. INTERFACE BETWEEN BIOPOLYMERS AND BIOLOGICAL ENVIRONMENT. THE MOST COMMONLY USED BIOPOLYMERS AND THEIR APPLICATION.
[+] DIT0006 BIOTRANSFORMATION OF XENOBIOTICS 45h
THE ELIMINATION OF XENOBIOTICS FROM THE ORGANISM DEPENDS UPON ITS CONVERSION TO HYDROSOLUBLE SUBSTANCES THROUGH BIOTRANSFORMATION, WHICH IS CONDUCTED THROUGH NON-SPECIFIC ENZYMES IN TWO STAGES. DURING THIS PROCESS, THE INTERMEDIATE PRODUCT MAY BE MORE TOXIC THAN THE UNCHANGED OR IT MAY OCCUR THE FORMATION OF REACTIVE OXYGEN SPECIES, WHICH ARE IMPLIED IN THE ACTION MECHANISM OF SOME TOXIC AGENTS. THIS COURSE IS AIMED AT STUDYING THE MOST IMPORTANT BIOTRANSFORMATION REACTIONS AND THEIR PARTICIPATION IN THE TOXIC ACTION MECHANISM.
[+] DIT0007 GOOD MANUFACTURING PRACTICES 15h
ANALYSIS OF THE TECHNICAL-SCIENTIFIC PRINCIPLES THAT GUIDE THE GOOD MANUFACTURING PRACTICES AND THEIR APPLICATION AND DOCUMENTATION IN THE DEVELOPMENT AND PRODUCTION OF MEDICINES, TAKING INTO ACCOUNT THE PERSPECTIVES OF INNOVATION OF PRODUCTS AND/OR PROCESSES.
[+] DIT0008 PHARMACOTECHNICAL DEVELOPMENT AND CONTROL OF PHYTOTHERAPEUTICALS 30h
STUDY OF THE SCIENTIFIC PRINCIPLES THAT GUIDE THE OPERATIONS AND THE PROCESSES OF TRANSFORMATION OF MEDICINAL PLANTS INTO MEDICINES, TAKING INTO CONSIDERATION LEGAL AND CULTURAL ASPECTS, THE PHARMACOTECHNICAL OPERATIONS INVOLVED AND THE QUALITY CONTROL METHODS.
[+] DIT0010 STUDY OF THE STABILITY OF MEDICINES 15h
THE COURSE AIMS TO ADDRESS ADVANCED THEMES APPLIED TO THE STUDY OF THE STABILITY OF MEDICINES. ADDRESSING ASPECTS RELATED TO THE INTERACTIONS AND INCOMPATIBILITIES IN DRUGS-EXCIPIENTS, DEGRADATION REACTIONS, KINETICS AND MATHEMATICAL MODELS APPLIED TO THE STUDY OF THE STABILITY OF PHARMACEUTICAL PRODUCTS. IN ADDITION TO ASSESSING THE APPLICATION OF THIS STUDY IN THE REGULATION, REGISTRATION AND COMMERCIALIZATION OF MEDICINES.
[+] DIT0011 ETHICS IN RESEARCH 15h
HISTORY ABOUT THE ETHICAL CONCEPTS OF RESEARCH WITH HUMAN BEINGS. ETHICAL PRINCIPLES OF THE RESEARCH WITH HUMAN BEINGS. NATIONAL AND INTERNATIONAL GUIDELINES PROPOSED FOR THE BIOMEDICAL RESEARCH WITH HUMAN BEINGS. ETHICAL AND LEGAL ASPECTS OF THE CLINICAL TESTS. BAD SCIENTIFIC CONDUCT IN PHARMACOLOGICAL-CLINICAL RESEARCH. SCIENCE, INDUSTRY AND CONFLICT OF INTERESTS. RESPONSIBILITIES OF THE NATIONAL COMMITTEE OF ETHICS IN RESEARCH (CONEP) AND OF THE COMMITTEES OF ETHICS IN RESEARCH (CEPS).
[+] DIT0020 NANOTECHNOLOGY APPLIED TO THE FORMULATION OF MEDICINES 30h
THROUGH THE STUDY OF THE METHODS OF OBTAINMENT AND CHARACTERIZATION OF THE PHYSICAL-CHEMICAL AND BIOLOGICAL PROPERTIES OF THE NANOPARTICULATE SYSTEMS, TO UNDERSTAND THE FUNCTIONING OF THESE SYSTEMS AND TO ASSESS BENEFITS IN RELATION TO THE TRADITIONAL PHARMACEUTICAL FORMS THAT EXIST IN THE MARKET. ASSESSMENT OF THE NANOTECHNOLOGY AS A MEANS OF SOLVING TECHNOLOGY-RELATED, STABILITY-RELATED, EFFICACY-RELATED AND SAFETY-RELATED PROBLEMS OF THE MEDICINES.
[+] DIT0021 EXPERIMENTAL ONCOLOGY 60h
TO KNOW THE MECHANISMS OF CARCINOGENESIS AND TO UNDERSTAND THE TUMORAL PROGRESSION AS A PROCESS OF CELL IMMORTALIZATION AND TRANSFORMATION UNTIL THE ACQUISITION OF THE INVASIVE OR METASTATIC PHENOTYPE, THROUGH CHANGES OF THE CONTROL MECHANISMS OF THE CELL CYCLE AND OF THE APOPTOSIS, IN ORDER TO ESTABLISH THE BASES FOR THE PREVENTION AND TREATMENT OF CANCER. TUMOR ANGIOGENESIS AND VASCULARIZATION. BEHAVIOR OF THE IMMUNE SYSTEM IN CANCER AND THE USE OF IMMUNOTHERAPY IN THE TREATMENT OF NEOPLASIAS. PROSPECTION OF THE BIODIVERSITY IN THE SEARCH FOR NEW ANTICANCER DRUGS. EXPERIMENTAL METHODS FOR THE ASSESSMENT OF THE ANTICANCER ACTIVITY OF NEW MOLECULES.
[+] DIT0022 RESEARCH, IDENTIFICATION AND CHARACTERIZATION OF NEW THERAPEUTIC TARGETS 60h
BIOACTIVE MOLECULES. ISOLATION OF MOLECULES, STRUCTURE OF MOLECULES ( HPLC, MASS SPECTROMETRY AND EDMAN DEGRADATION SEQUENCING). THREE-DIMENSIONAL STRUCTURES (X-RAY DIFFRACTION, CIRCULAR DICHROISM). SYNTHESIS OF MOLECULES. IMMUNOBIOCHEMICAL TECHNIQUES: ELISA, WESTERN BLOT, SOUTHERN BLOT, NORTHERN BLOT, ONE AND TWO-DIMENSIONAL ELECTROPHORESIS, POLYMERASE CHAIN REACTION, REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION. BIOLOGICAL ACTIVITY OF MOLECULES. USE OF MOLECULES AS PHARMACEUTICALS.
[+] DIT0023 PREFORMULATION OF PHARMACEUTICAL DOSAGE FORMS 30h
INTEGRATION OF KNOWLEDGE OF CHEMISTRY, PHYSICAL-CHEMISTRY AND PHARMACEUTICAL TECHNOLOGY IN THE DISCUSSION OF THE PHYSICAL-CHEMICAL PROPERTIES OF DRUGS AND THEIR INFLUENCE ON THE PREPARATION, STABILITY AND BIOAVAILABILITY OF MEDICINES. STUDY OF THE INTERACTIONS BETWEEN DRUGS AND EXCIPIENTS AND THEIR CONSEQUENCES ON THE BIOAVAILABILITY AND STABILITY OF MEDICINES THROUGH EXAMPLES OF PRE-FORMULATION EXPERIMENTS.
[+] DIT0026 PROTEOMICS 30h
PROTEOMICS IS A SET OF EXTRAORDINARILY USEFUL TECHNOLOGIES FOR THE STUDY OF THE PROTEIC CONTENT OF THE BIOLOGICAL SYSTEMS. THE KNOWLEDGE OF ALL THE PROTEINS EXPRESSED BY A GENOME, WHICH HAS BEEN DESIGNATED AS PROTEOME, HAS DRAWN A LOT OF INTEREST FROM THE PHARMACEUTICAL INDUSTRY, WHICH ARE THE FIRST TO MAKE STRONG INVESTMENT IN THE PROGRAMS (GENOME, PROTEOME, TRANSCRIPTOME, METABOLOME, PHARMACOGENOME, ETC) WITH THE GOAL OF INTRODUCING TECHNOLOGICAL INNOVATION IN HEALTH. THUS, THE IDENTIFICATION OF BIOLOGICAL MARKERS OF THE DISEASES (ENZYMES, SUBSTRATES, RECEPTORS, ETC) MAY LEAD TO CONDITIONS OF DEVELOPING SPECIFIC MEDICINES THAT MAY REGULATE ITS ACTIVITY IN DISEASES. THE GOAL OF THIS COURSE SHALL BE THE KNOWLEDGE OF THE ** ???? *** AND OF TECHNIQUES THAT REVEAL THE PARTICIPATION OF GENES (DNA) IN PATHOLOGICAL SITUATIONS, WHOSE EXPRESSION (PROTEINS) MAY BE INCREASED OR REDUCED. IT SHALL BE DISCUSSED THE TECHNOLOGY THAT ENABLES PROTEOMICS AND THE PARTICIPATION OF THE PHARMACEUTICAL INDUSTRY IN THE DEVELOPMENT OF SPECIFIC MEDICINES FOR THE TREATMENT OF HUMAN DISEASES.
[+] DIT0028 MEDICINAL CHEMISTRY 60h
ASPECTS OF THE DISCOVERY, DESIGN AND DEVELOPMENT OF MEDICINES. MAIN MECHANISMS OF ACTION OF DRUGS. BASIC NOTIONS OF QUANTITATIVE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND MAIN STRUCTURAL MODIFIERS. MECHANISMS OF ACTION AND SYNTHESIS OF THE MAIN CLASSES OF DRUGS.
[+] DIT0029 SEMINARS IN RESEARCH AND DEVELOPMENT OF MEDICINES 15h
DISCUSSION OF SCIENTIFIC PAPERS AND CURRENT THEMES RELATED TO THE DEVELOPMENT AND TECHNOLOGICAL INNOVATION IN MEDICINES THROUGH LECTURES, MEETINGS, WORKSHOPS AND OTHER ACTIVITIES.
[+] DIT0032 ADVANCED TOPICS IN THE RESEARCH AND DEVELOPMENT OF MEDICINES 30h
CONFERENCES, LECTURES, SEMINARS AND WORKSHOPS SHALL BE GIVEN BY RENOWNED VISITING PROFESSORS OR BY PROFESSORS OF THE MEMBER HIGHER EDUCATION INSTITUTIONS, OR BY ACCLAIMED PROFESSIONALS OF THE AREA WITH THE GOAL OF ENCOURAGING THE POSTGRADUATE STUDENTS' KNOWLEDGE IN CURRENT THEMES RELATED TO THE PROGRAM'S FOCUS. TO ENCOURAGE THE DEVELOPMENT OF THE SCIENTIFIC THINKING THROUGH THE DISCUSSION OF THE THEMES TO BE PRESENTED.
[+] DIT0034 SPECIAL TOPICS IN TECHNOLOGICAL INNOVATION IN MEDICINES 30h
VARIABLE SYLLABUS, ACCORDING TO THE NEED OF THE ONGOING PROJECTS IN THE PROGRAM.
[+] DIT0036 EXPERIMENTAL PSYCHOPHARMACOLOGY 45h
THIS COURSE IS AIMED AT PRESENTING AND DISCUSSING THE MAIN CLASSES OF PSYCHOACTIVE DRUGS AND AT THE SAME TIME PROVIDING THE STUDENT WITH A DIRECT CONTACT WITH SOME USUAL METHODOLOGIES AND THEIR FOUNDATIONS THAT ENABLE THE ASSESSMENT OF THE POSSIBLE EFFECTS OF PLANT-ORIGIN DRUGS AND/OR PRODUCTS OR OF DRUGS AND/OR PRODUCTS OBTAINED BY SYNTHETIC ROUTE ON THE CENTRAL NERVOUS SYSTEM. APPLICATION OF PSYCHOPHARMACOLOGY AS A TOOL OF RESEARCH AND DEVELOPMENT OF EXPERIMENTAL PROTOCOLS IN PSYCHOPHARMACOLOGY. CEREBRAL NEUROTRANSMISSION SYSTEMS AND RELATED PSYCHOPATHOLOGIES. THE ACTION/ACTIVITY OF DRUGS IN NEUROTRANSMISSION. PHARMACOKINETICS OF THE CENTRAL ACTION DRUGS. PSYCHOPHARMACOLOGY AND BEHAVIOR. PSYCHOPHARMACOLOGY AS A TOOL FOR THE STUDY OF THE PHYSIOLOGICAL PROCESSES. RESEARCH IN PSYCHOPHARMACOLOGY: PROJECTS, PROTOCOLS AND PUBLICATIONS IN THE AREA.
[+] DIT0040 PHARMACOTHERAPY TOPICS 30h
STUDY OF THE RATIONAL THERAPEUTICS AND EVIDENCE-BASED MEDICINE. CLINICAL PHARMACOLOGY IN SPECIAL POPULATIONS (ELDERLY, CHILDREN, PREGNANT WOMEN, NURSING MOTHER AND INFANT, PATIENTS/USERS WITH LIVER OR KIDNEY PROBLEMS). PHARMACOGENETICS. DRUG INTERACTIONS. ADVERSE REACTIONS CAUSED BY DRUGS. DISEASES AND THEIR THERAPEUTICAL TARGETS OF INTEREST OF THE POSTGRADUATE PROGRAM IN DEVELOPMENT AND TECHNOLOGICAL INNOVATION IN MEDICINES (PPGDITM) FROM THE ISOLATED AND ARTICULATED PROJECTS OF THE PROGRAM.
[+] DIT0043 POST-COMMERCIALIZATION STUDY OF MEDICINES 30h
THEORY AND DEFINITION OF SAFETY OF MEDICINES, REGULATORY ASPECTS AND HARMONIZATION, THE ROLE OF THE REGULATORY AGENCIES, OF THE PHARMACEUTICAL INDUSTRY, OF THE HEALTH PROFESSIONALS AND OF THE CONSUMERS, METHODOLOGY AND IMPACT OF THE POST-COMMERCIALIZATION STUDIES.
[+] DIT0044 SUPERCRITICAL TECHNOLOGIES APPLIED TO NATURAL PRODUCTS 30h
INTRODUCTION, FUNDAMENTAL CONCEPTS AND CONTEXTUALIZATION. APPLICATION OF THE SUPERCRITICAL TECHNOLOGY IN THE OBTAINMENT OF BIOACTIVE COMPOUNDS. PROPERTIES OF THE SUPERCRITICAL FLUIDS. SUPERCRITICAL EXTRACTION PROCESS. USED SOLVENTS. SOLUBILITY OF THE CONSTITUENTS IN CO2-SC. SUPERCRITICAL EXTRACTION OF MEDICINAL PLANTS AND FUNCTIONAL FOOD. OBTAINMENT OF BIOACTIVE COMPOUNDS.
[+] DIT0045 SCIENTIFIC PAPER WRITING 30h
THE IMPORTANCE OF PUBLISHING RESULTS. PROFILE OF THE MOST ADEQUATE JOURNAL FOR PUBLICATION AND SELECTION OF THE MAGAZINE. TYPES OF PAPERS AND SELECTION OF THE BEST FORM OF PRESENTATION. LANGUAGE OF THE PUBLICATION. ITEMS THAT MAKE UP EACH TYPE OF PAPER, SUCH AS: FULL PAPER, SHORT COMMUNICATION AND REVIEW ARTICLES. DISCUSSION ON THE IMPACT INDEX (J, H, OTHERS) AND ON THE QUALITY OF THE JOURNALS, ACCORDING TO CAPES'S QUALIS. DISCUSSION ON THE JOURNALS' INSTRUCTIONS TO THE AUTHORS: JOURNALS' RULES. TEMPLATE OF A FORWARDING AND REPLY LETTER AND ARTICLE FOR PUBLICATION. WRITING OF THE DRAFT OF THE PAPER TO BE PUBLISHED, IDENTIFYING THE MOST IMPORTANT INFORMATION. WRITING OF THE PAPER'S INTRODUCTION. REFERENCES. WRITING OF THE MATERIALS AND METHODS. DISCUSSION OF THE RESULTS AND CONCLUSION. CRITICAL ANALYSIS OF AN ARTICLE PUBLISHED IN A HIGH IMPACT JOURNAL IN THE STUDENT'S FIELD OF STUDY.
[+] DIT0046 STEREOCHEMISTRY OF PHARMACEUTICALS 60h
FUNDAMENTAL AND ADVANCED ASPECTS OF STEREOCHEMISTRY, ENCOMPASSING THE STEREOCHEMISTRY OF CYCLIC COMPOUNDS, ATROPOISOMERY, CAHN-INGOLD-PRELOG SYSTEM, EZ ISOMERY, CHIRAL SEPARATIONS, MAIN MODELS OF ASYMMETRIC INDUCTION, FELKIN-AHN, CRAM, ETC. IMPORTANCE OF THE CHIRALITY IN THE ACTION AND METABOLISM OF DRUGS. OBTAINMENT OF CHIRAL DRUGS: SYNTHESIS, NATURAL PRODUCTS AND BIOTRANSFORMATION. ANALYTICAL METHODS FOR THE IDENTIFICATION OF STEREOISOMERS. STEREOCHEMISTRY APPLIED IN DIFFERENT PHARMACEUTICAL CLASSES: A-ADRENERGIC, ANTIHYPERTENSIVE, ANTI-INFLAMMATORY, ANTIMALARIC, ANTICOAGULANT, ANTINEOPLASIC, ANTIBIOTIC AND DISCUSSION OF PAPERS FROM JOURNALS.
[+] DIT0047 ORGANIC SYNTHESIS IN THE OBTAINMENT OF DRUGS 60h
INTRODUCTION: DRUGS/PHARMACEUTICALS - SOURCES. COSTS. DISCOVERY AND DEVELOPMENT: ORIGIN AND SITUATION IN BRAZIL. STRATEGIES FOR THE SYNTHESIS OF DRUGS. PLANNING OF SYNTHETIC ROUTES. SYNTHESIS OF SOME CURRENT DRUG CATEGORIES. DISCUSSION OF PAPERS FROM JOURNALS. DEVELOPMENT OF A PROJECT OF SYNTHESIS OF A DRUG OF SOCIAL INTEREST (GENERIC OR NOT). PRESENTATION AND DISCUSSION OF THE DEVELOPED PROJECT.
[+] DIT0048 FOUNDATIONS OF SPECTROMETRIC ANALYSIS - MAGNETIC RESONANCE 60h
MOLECULAR GEOMETRY, INTRA AND INTERMOLECULAR FORCE. THE ELECTROMAGNETIC SPECTRUM AND GENERAL ASPECTS OF THE LIGHT-MATTER INTERACTION. FOUNDATIONS OF MOLECULAR SPECTROSCOPY OF NUCLEAR MAGNETIC RESONANCE.
[+] DIT0049 ADVANCED TOPICS IN RESEARCH & DEVELOPMENT OF MEDICINES II 45h
VARIABLE, ACCORDING TO THE NEED OF THE PROGRAM'S ONGOING PROJECTS.
[+] DIT0050 ADVANCED TOPICS IN RESEARCH & DEVELOPMENT OF MEDICINES III 15h
VARIABLE SYLLABUS, ACCORDING TO THE NEED OF THE PROGRAM'S ONGOING PROJECTS.
[+] DIT0051 ADVANCED TOPICS IN RESEARCH & DEVELOPMENT OF MEDICINES IV 30h
VARIABLE SYLLABUS, ACCORDING TO THE NEED OF THE PROGRAM'S ONGOING PROJECTS.
[+] DIT0052 ADVANCED TOPICS IN RESEARCH AND DEVELOPMENT OF MEDICINES V 30h
VARIABLE CONTENT ACCORDING TO THE NEED OF THE PROJECTS UNDER DEVELOPMENT IN THE PROGRAM.

 

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EMENTAS DE DISCIPLINAS:

DIT0047 - SÍNTESE ORGÂNICA NA OBTENÇÃO DE FÁRMACOS

DIT0046 - ESTEREOQUÍMICA DE FÁRMACOS

 

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